ESPE Abstracts

Background: Gigantism is a condition characterized by excessive growth and height significantly above average; it is usually caused by a tumor on the pituitary gland. In some cases the condition can be passed on genetically through a mutated gene.Objective and hypotheses: Describe clinical, hormonal, and morphological profile of seven children with gigantism. Mean age=14 years (9–16), age of onset of symptoms 12 years. Tall stature (50%), and brain ...

Background: True diabetes insipidus (DI) is a rare disease in children, defined as the excretion of hypotonic urine and polydypsia, secondary to an absolute or relative deficiency of antidiuretic hormone arginine vasopressin (central DI) or a resistance to the action of this hormone (nephrogenic DI). To differentiate from primary polydypsia.Objective and hypotheses: We report the case of AM a 13 years old girl, with personal history of cholecystectomy at...

Background: Central diabetes insipidus (DIC) is usually the final result of lesions affecting the hypothalamic–neurohypophyseal system, for the children, germinoma is the main reason. The MRI aspect is often limited to thickness pituitary stalk with loss of hyperintensity of the neurohypophysis.Objective and hypotheses: Thickening of pituitary stalk is suggestive of germinoma, the clinical picture is dominated by a DIC (90%), associated to hypopitui...

Introduction: Lesional hypothalamic obesity is most frequently attributable to craniopharyngiomas. The aim of our work is to describe the modalities of occurrence of this complication in a series of 27 children with craniopharyngioma followed in our center. We carried out a descriptive retrospective study of 27 cases of craniopharyngioma in children followed in the endocrinology department of the CPMC over a period of 16 years.Re...

Objectives: childhood growth influences their social and psychological behavior, and abnormal growth may reflect underlying pathological etiologies. We aim to study etiologies and carachteristics of short stature in children in endocrinology department.Methods: 160 children ranging from 2 years to 21 years with short stature were retrospectively studied.Results: In this study, a di...